Javelina, Lil Gun seems to be a powder similar to W296 or H110. Small charges of W296 or H110, can cause detonation and blow the gun up, or at the least, poor ignition. When the change is large enough, and the pressure high enough, to prevent detonation and get proper ignition, the pressure would be to high. If Lil Gun does burn the same as W296 or H110, I don't know, but be carefull. The fact that Hodgdon doesn't recommend it for reduced loads, tells you something. There are many powders that are safe for reduced loads. Small capacity cases like the 22 Hornet use Lil Gun, W296, or H110 because the case is nearly full and it burns properly. Using Lil Gun for reduced loads could be dangerous.