I've done a fair amount of teaching with handguns over the years, mostly women and kids, and my number one rule is to find a gun their hand likes. If it's not comfortable to them, they simply won't shoot it well. With each new student I laid all the handguns on the table, and told them to pick the one that felt the best. Several of my revolvers wore Pachmayr Compac grips, and nearly ALL the smaller-statured shooters picked the guns that wore them. In fact, I even modifed a couple guns to let them use that grip. So I guess it's no surprise that every handgun I own fits me well. My favorite carry gun is a Smith M-65 3-inch, six rounds of 38+P GDHP or 357/125 HP is a comforting payload. But other times I carry my Bersa .380 with Rem. Golden Sabres, and while it's not the ballistic equal of the 38/357, eight rounds properly delivered should quickly end any Serious Social Situation.
One thing I always stressed with new shooters is that they should worry less about ballistics, and pay more attention to carrying a gun they shot well. Confidence with small arms can make a lot of difference in the attitude of the carrier! If it hurts to shoot, or they don't shoot it well, they'll be much more hesitant to bring it in to play. But if they're confident, properly trained, and see the threat coming, they are a force to be reckoned with!