It's whatever works for you. I personally really would like to have a korth 357. However unlike my my Buddy Jimmy who has one I didn't become a millionaire the second my mommy died. They are nice though.
For me it would either be my 686-4 4 inch or my GP100 4 inch. I now have the trigger reworked in the GP100 to the point where it's as good as the 686's trigger. Never had a Python but never saw one last past 20,000 rounds without developing timing issues. I would like to try the Kimber but have a 2.5 inch SP101 that covers the same purpose and I can shoot it well.
The one revolver that I have zero interest in is the Rhino. Man those things are ugly! I have thought that about other guns that eventually grew on me but the Rhino doesn't stand a chance.....I just ain't interested.
Ah Grandpa, after reading most of this ten year old thread it is interesting to see how it fluctuates.
What is best, for one who will use it often it is what ever fits his needs best; for absolute fit, finish and accuracy Korth, Manurhin and Janz are as good as it gets.
Some people who work on firearms say the Manurhin M73, not Ruger redo, is better construction than Korth.
Janz is a development off of Korth , when Korth was bankrugt, and is about as good as it gets,period.
I have a Manurhin former Police revolver and from the way it recoils, I can see why it has high class soft grips.
As far as the best, strongest all around revolver, the Colt New Service probably should rank at top.
I have one with two cylinders.
That is what Colt should bring back, not that kinda-sorta Python they did.