The important thing here is to have the projectile seated against the powder charge. Take note of where the ramrod stops, and then run it into an empty chamber. If it goes further, you know you've seated the projectile fully.
As for how deep it seats, that will vary by load and projectile. If you want it closer to the rifling, you can double the wad, add powder, or use a filler.
It's been a very long time since I used pyrodex, as I just didn't like it, but, BP likes a little compression.
They say wonder wads will prevent chain fire, but I'd consider greasing the front anyway, or lubing the wads.
I used to use a pair of 1860 44s for cas. I used conicals with lubed grooves over 30gr of 2f. I also chamfered the cylinder mouths, so instead of shaving lead, they would swage into the cylinder. That would work with round ball also. Tighter fit, better seal.
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