With 44mag I limit myself to 100 yards. I'm sure it will kill deer at longer distances, but 100 is the farthest I trust myself to aim it in the field. sighted in at 100, I'm an inch high at fifty, and an inch low at 115. My range estimation isn't all that good, and this gives me a little bit of room for error. On a known distance at a shooting range, it is fun and very possible to hit targets at longer ranges. But beyond a 100 yards, that bullet is dropping pretty fast, and range estimation is critical, more than I am able to do in the hunting field.
Duane