You use GCs when the mould you are using is cut for them. I never had any luck using a GC design without the GC.
Were I loading for that Marlin .444, I would only use PB bullets for plinkers down in the 1200-1400 fps range. I like Red Dot for such work because it bulks up so well.
There is an exception, though. I am one of those who will cheerfully use fillers in a straight wall case. Years back, I was shooting a Siamese Mauser in .45-70. Had a Lee 405 grain PB HP mould and a LOT of AA 5744. I took to dumping a charge into the case, nearly filling the case with cornmeal and seating the bullet. I started low and worked to a load in the 1800 fps range. No problems, good accuracy. I figger the compressed cornmeal worked as a gascheck for the PB bullet.
A more sensible fellow would have just bought a GC mould.