HoCoMDHunter - You're right trial and error does take years, but so does organized development. I take what weight bullet I want to shot, then pick a powder and do a load ramp with it (starting at minimun published data and working up in .x grains to max.), after I find the "best" combination of powder/bullet, I'll start adjusting COL(AOL) to shrink groups. Then I'll start weeding cases by weight, bullets by weight - not really neccesary, but adds to the consistency. Then I'll do the same except change primers, then again w/another powder. This does take me years, and a lot of reloading. Isn't that why we handload? There are many other ways to find the optimal load for a given gun that are faster, but IMHO they limit your knowledge of what's available. You will find a "good" load early on with this proceedure, and may want to pick one powder/bullet/primer combo and work with that.