Win 296 is the only powder I load in my hot handgun loads. The reason is because I can buy it cheaper than H-110. I have used both and did find them interchangable and very accurate. I also have some boxes of ammo got set back and not shot for years, but have never had a problem with H-110 or Win.-296 and have shot some that was loaded more than 15 yrs. pryer to fireing.